Prolongation of survival in metastatic melanoma after active specific immunotherapy with a new polyvalent melanoma vaccine - PubMed

Traditionally, melanoma was a death sentence (let alone metastatic melanoma). Here, having complete regression in some patients is incredible. 

"Induction of cell-mediated and humoral immune responses to common melanoma-associated antigens present on autologous melanoma cells was observed in patients ...Of 40 patients with evaluable disease, nine (23%) had regressions (three complete)."

https://pubmed.ncbi.nlm.nih.gov/1417196/