Monday, September 7, 2020

Invermectin as possible treatment for COVID

"cells infected with the SARS-CoV-2 or COVID-19 virus were exposed to 5 µM ivermectin in 48 h, and a 5000-fold reduction in viral RNA compared with control...the drug may have antiviral effects by inhibiting the importin (IMP) α/β receptor, which is responsible for transmitting viral proteins into the host cell nucleus."
"The blood levels of ivermectin at safe therapeutic doses are in the 20–80 ng/ml range, while the activity against SARS-CoV2 in cell culture is in the microgram range. "
https://www.nature.com/articles/s41429-020-0336-z

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