high dose (40 mg/kg) oral acetaminophen for BMT
"All 60 min plasma concentrations were ≥ 70 μmol·l–1 (ED50 for adenotonsillectomy) and less than 800 μmol·l–1 (associated with toxicity)"
http://onlinelibrary.wiley.com/doi/10.1046/j.1460-9592.2002.00743.x/abstract
acetaminophen 60 mg/kg and 90 mg/kg paracetamol in fit young adult patients undergoing third molar extractions
"90 mg/kg dose, though safe, does not offer any advantages over 60 mg/kg dose"
http://www.ncbi.nlm.nih.gov/m/pubmed/18020073/
High dose acetaminophen 40 mg/kg was better than 100 mg/kg [Wow!!]
"High dose acetaminophen (100 mg/kg) was no more effective than 40 mg/kg and was associated with increased nausea and vomiting. "
https://sciencescape.org/paper/11758634
High dose acetaminophen premed for kids having BMT.
[RCT 0,20,40 mg/kg Signif less rescue narcotic at either dosage, and 20 min longer duration and less rescue antiemetic for the high-dose group.]
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511941/
Wednesday, July 30, 2014
Fwd: Better mental state with spinal anesthesia with no sedation
General or spinal anesthesia: which is better in the elderly?
Chung F, et al. Anesthesiology. 1987.
http://www.ncbi.nlm.nih.gov/m/pubmed/3307537/
Anaesthesia for hip fracture surgery in adults.
Cochrane Database Syst Rev. 2016
...comparison of regional versus general anaesthesia for hip (proximal femoral) fracture repair in adults...We did not find a difference between the two techniques, except for deep venous thrombosis in the absence of potent thromboprophylaxis... large randomized trials reflecting actual clinical practice are required before drawing final conclusions. PMID 26899415
Anaesthesia for hip fracture surgery in adults.
Cochrane Database Syst Rev. 2016
...comparison of regional versus general anaesthesia for hip (proximal femoral) fracture repair in adults...We did not find a difference between the two techniques, except for deep venous thrombosis in the absence of potent thromboprophylaxis... large randomized trials reflecting actual clinical practice are required before drawing final conclusions. PMID 26899415
Confirmed in one study:
Not confirmed in other studiesBetter mental state with spinal anesthesia with no sedation
https://link.springer.com/content/pdf/10.1007/BF03005334.pdf
"A significant intragroup difference between preoperative and postoperative MMS score was detected in the GA group"
"A significant intragroup difference between preoperative and postoperative MMS score was detected in the GA group"
Wednesday, July 23, 2014
Evaluating informed consent obtained by surgical residents.
Not the result I was expecting when I looked up this study.
"Ninety-nine per cent of patients reported that the resident adequately described the procedure and nine per cent had additional questions for the attending physician. Major surgery-specific complications were discussed with 89 per cent of patients. Benefits of the procedure were discussed with 96 per cent and alternatives with 85 per cent of patients. Residents received an overall grade of excellent (74% of patients), good (25%), or fair (1%)."
http://www.ncbi.nlm.nih.gov/m/pubmed/24887738/
"Ninety-nine per cent of patients reported that the resident adequately described the procedure and nine per cent had additional questions for the attending physician. Major surgery-specific complications were discussed with 89 per cent of patients. Benefits of the procedure were discussed with 96 per cent and alternatives with 85 per cent of patients. Residents received an overall grade of excellent (74% of patients), good (25%), or fair (1%)."
http://www.ncbi.nlm.nih.gov/m/pubmed/24887738/
| Hope WW, Walters K, Bools LM, Adams A, Hooks WB 3rd, Clancy TV. | Related Articles | |
| Evaluating informed consent obtained by surgical residents. | ||
| Am Surg. 2014 May;80(5):522-4. | ||
| PMID: 24887738 | ||
Sunday, July 20, 2014
Cool trailers
Cricket, Alto Safari, UEV440, Diubleback
http://youtu.be/eqhsfrM96SQ
http://youtu.be/OssiS9Rpo98
http://youtu.be/XxvfDTaUVAo
http://youtu.be/GIG9P0lB1iA
http://youtu.be/eqhsfrM96SQ
http://youtu.be/OssiS9Rpo98
http://youtu.be/XxvfDTaUVAo
http://youtu.be/GIG9P0lB1iA
Saturday, July 5, 2014
How text-to-speech is made
To say the word "impressive" the voice engine stitches together parts of the words "important," "president," and "detective" from recordings of a boy reading words.
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