Tuesday, October 30, 2012

Bus transit directions on iPhone 5

www.google.com/transit
This web page works great on the iPhone for finding bus times and routes just like you could on the old iPhone maps app using google maps. 

Sent from my iPhone

Monday, October 29, 2012

From "Moments with Mark"

"What stops me in my tracks is realizing how little I control of God's plan
for my life, yet how important it is for me to be responsible for that which
I can control - choices."

Saturday, October 27, 2012

Residential Swimming Pool Heating with Geothermal Heat Pump Systems

"A simple economic analysis showed that it would not be feasible to incorporate a swimming pool into a GHP system in northern U.S. climates due to the extra ground loop required. On the contrary, immediate savings could be realized in southern U.S. climates."


Sent from my iPhone

Geothermal Heat Pump Resource - Everything Geothermal - Home

http://www.geothermal-heat-pump-resource.org/

Thursday, October 25, 2012

Sunday, October 21, 2012

Welcome to Foldit!!

This online game actually helps scientists figure out what shape a given protein sequence folds into. Players tweak the protein shape, while the server computes the overall energy of the chemical interactions in the entire protein, with the underlying assumption that a protein ends up in its lowest possible energy configuration.

http://youtu.be/lGYJyur4FUA


Ribosome kinetics and aa-tRNA competition determine rate and fidelity of peptide synthesis

As my daughter and I studied biology, we wondered how on earth a prokaryote cell can assemble a protein at a mind-boggling 20 amino acids per second. We wondered what the rate limiting step was. 
This paper discusses a mathematical model to prove that the rate-limiting factor when a ribosome is assembling a protein is the time it takes for a near-match amino acid to get shouldered out of the way by a correct-match amino acid in the chemical shuffle of building blocks arriving at the protein assembly site.

http://digitalcommons.unl.edu/cgi/viewcontent.cgi?article=1008&context=cbmeviljoen

Irreducible complexity and evolution

An interesting treatise exploring how it could have been possible for random events in primordial evolutionary history to give rise to something as incredibly complex as protein synthesis via translation of a genetic code. 
"Indeed, the translation system might appear to be the epitome of irreducible complexity because, although some elaborations of this machinery could be readily explainable by incremental evolution, the emergence of the basic principle of translation is not. Indeed, we are unaware of translation being possible without the involvement of ribosomes, the complete sets of tRNA and aminoacyl-tRNA synthetases (aaRS), and (at least, for translation to occur at a reasonable rate and accuracy) several translation factors. In other words, staggering complexity is inherent even in the minimally functional translation system. Thus, as outlined above, it appears that the evolutionary origin of translation is to be sought along the exaptation route, i.e., by retrodiction of the ancestral functions of various components of the translation system that would allow them to evolve functionalities enabling their recruitment for translation.
Even this, however, does not do the full justice to the difficulty of the problem. The origin of translation appears to be truly unique among all innovations in the history of life in that it involves the invention of a basic and highly non-trivial molecular-biological principle, the encoding of amino acid sequences in the sequences of nucleic acid bases via the triplet code[15,16]. This principle, although simple and elegant once implemented, is not immediately dictated by any known physics or chemistry (unlike, say, the Watson-Crick complementarity) and seems to be the utmost innovation of biological evolution."

Tuesday, October 16, 2012

Dictionary

Word Origin & History for
"hidebound"
hidebound 1550s, from hide (n.1) + past tense of bind. Original reference is to emaciated cattle with skin sticking closely to backbones and ribs; metaphoric sense of "restricted by narrow attitudes" is first recorded c.1600.

Youtube - a day in the life

Nicely edited vignettes of lives all around the world on a single day.


Car Crash - you get no warning!

Think about defensive driving for each of these scenarios - pretty hard to avoid some of them. Many of them caused by someone rushing to pass a slow vehicle or run a yellow light.

http://youtu.be/VeN7zJhtg60

Saturday, October 13, 2012

Travel websites

http://frugaltraveler.blogs.nytimes.com/2012/10/09/10-travel-web-sites-worth-bookmarking/

Dishtip.com by single dish, not by restaurant
Skypicker.com figure out where you can fly within your budget
Stay.com listings of top attractions, museums, shopping, restaurants by destination
Staydu.com matches hosts from around the world with travelers
Vayama.com flight search engine that specializes in international routes 
Trivago.com compare many hotel sites at once
Matadornetwork.com free online travel community whose site contains treasure troves of articles
Seat61.com  tickets for any European train journey at the cheapest price
Triptuner.com use a panel of six sliders to “tune” your trip
Expatsblog.com/blogs


Crazy mountain bike skills



Danny McAskill
He's in the new movie Premium Rush. He's the only good part of it.
http://www.imdb.com/title/tt1547234/

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